BTLA antibody

Catalog No. ABIN7278524

Product Details anti-BTLA Antibody

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This BTLA antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Purification: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

Clone: 6A6

Isotype: IgG

Application Details

Comment:

0.5 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10  mM NaH2PO4, 150  mM NaCl, 0.09 %  Sodium azide,  pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

Expiry Date: 12 months

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: CD272 (BTLA Products)

Synonyms: BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody

Background: The 6A6 antibody reacts with mouse CD272, a type 1 transmembrane glycoprotein and member of the Ig superfamily. CD272, also known as BTLA (B and T Lymphocyte Attenuator), is expressed on peripheral lymphocytes as well as developing B and T cells, macrophages, and dendritic cells. CD272 is a receptor for CD270 (HVEM) and is structurally similar to CD152 (CTLA-4) and CD279 (PD-1) and functions as a negative regulator of B and T cell responses.

Gene ID: 208154

UniProt: Q3U0X8

Pathways: Cancer Immune Checkpoints