APOE antibody (Biotin)
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- Target See all APOE Antibodies
- APOE (Apolipoprotein E (APOE))
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Reactivity
- Human, Non-Human Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This APOE antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, ELISpot
- Specificity
- Native and recombinant apolipoprotein E (isoforms apoE2, apoE3 and apoE4).
- Cross-Reactivity (Details)
- The monoclonal antibody cross-reacts with apoE from non-human primates.
- Purification
- Purified from in vitro cultures by protein G affinity chromatography.
- Immunogen
- Purified human apolipoprotein E
- Clone
- E887
- Isotype
- IgG1
- Top Product
- Discover our top product APOE Primary Antibody
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- Application Notes
- For quantification of apoE in serum/plasma samples and cell culture supernatants using ELISA and for enumeration of human apoE producing cells using ELISpot. E887 is recommended as detection mAb in combination with coating mAb E276 . The antibody is also suitable for immunoprecipitation and Western blot.
- Comment
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Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
- Expiry Date
- 18 months
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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
: "Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins." in: Journal of virology, Vol. 88, Issue 21, pp. 12644-55, (2014) (PubMed).
: "ApoE production in human monocytes and its regulation by inflammatory cytokines." in: PLoS ONE, Vol. 8, Issue 11, pp. e79908, (2014) (PubMed).
: "Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice." in: Atherosclerosis, Vol. 227, Issue 1, pp. 58-64, (2013) (PubMed).
: "Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 303, Issue 9, pp. R903-8, (2013) (PubMed).
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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).
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- Target
- APOE (Apolipoprotein E (APOE))
- Alternative Name
- apoE (APOE Products)
- Synonyms
- ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
- Gene ID
- 348
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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