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HTRA2 antibody (AA 231-330) (AbBy Fluor® 350)

HTRA2 Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN6976978
  • Target See all HTRA2 Antibodies
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Binding Specificity
    • 15
    • 14
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 231-330
    Reactivity
    • 111
    • 71
    • 67
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 98
    • 14
    Rabbit
    Clonality
    • 90
    • 22
    Polyclonal
    Conjugate
    • 44
    • 10
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HTRA2 antibody is conjugated to AbBy Fluor® 350
    Application
    • 69
    • 47
    • 32
    • 25
    • 25
    • 18
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HTRA2
    Isotype
    IgG
    Top Product
    Discover our top product HTRA2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Alternative Name
    HTRA2 (HTRA2 Products)
    Synonyms
    CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
    Background

    Synonyms: Serine protease HTRA2, mitochondrial, HTRA2, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25 Serine proteinase OMI, HTRA2, OMI, PRSS25

    Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

    Gene ID
    27429
    UniProt
    O43464
    Pathways
    Positive Regulation of Endopeptidase Activity
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