IL4 Receptor antibody (AA 111-210) (Biotin)
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- Target See all IL4 Receptor (IL4R) Antibodies
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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Binding Specificity
- AA 111-210
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL4 Receptor antibody is conjugated to Biotin
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from rat IL-4R
- Isotype
- IgG
- Top Product
- Discover our top product IL4R Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Alternative Name
- IL-4R (IL4R Products)
- Synonyms
- IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
- Background
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Synonyms: Interleukin-4 Receptor, 582J2.1, CD124, CD-124, CD 124, IL 4R alpha, IL4RA, Interleukin 4 receptor alpha chain, MGC118473.
Background: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq, Jul 2008].
- Gene ID
- 25084
- UniProt
- Q63257
- Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process
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