Thyroglobulin antibody
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- Target See all Thyroglobulin (TG) Antibodies
- Thyroglobulin (TG)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Thyroglobulin antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein within C-terminal human Thyroglobulin.
- Clone
- 2H4
- Isotype
- IgG
- Top Product
- Discover our top product TG Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- Thyroglobulin (TG)
- Alternative Name
- Thyroglobulin (TG Products)
- Synonyms
- TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
- Background
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Synonyms: AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody, THYG_HUMAN antibody, Thyroglobulin antibody
Background: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
- Gene ID
- 7038
- UniProt
- P01266
- Pathways
- Thyroid Hormone Synthesis
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