Src antibody (pTyr419)

Catalog No. ABIN6989929

Product Details anti-Src Antibody

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Binding Specificity: pTyr419

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Src antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic phospho-Peptide corresponding to residues surrounding Tyr419 of human Src.

Clone: 8C13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Alternative Name: Src (Src Products)

Synonyms: AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody

Target Type: Viral Protein

Background:

Synonyms: ASV antibody, Avian sarcoma virus antibody, c SRC antibody, CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody, cSrc antibody, EC 2.7.10.2 antibody, Neuronal CSRC tyrosine specific protein kinase antibody, Neuronal SRC antibody, Oncogene SRC antibody, OTTHUMP00000174476 antibody, OTTHUMP00000174477 antibody, p60 Src antibody, p60-Src antibody, p60Src antibody, pp60c src antibody, pp60c-src antibody, pp60csrc antibody, Proto oncogene tyrosine protein kinase Src antibody, Proto-oncogene c-Src antibody, Proto-oncogene tyrosine-protein kinase Src antibody, Protooncogene SRC antibody, Protooncogene SRC Rous sarcoma antibody, Src antibody, SRC Oncogene antibody, SRC proto oncogene non receptor tyrosine kinase antibody, SRC_HUMAN antibody, SRC1 antibody, Tyrosine kinase pp60c src antibody, Tyrosine protein kinase SRC 1 antibody, Tyrosine protein kinase SRC1 antibody, v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody, V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody, v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody

Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene ID: 6714

UniProt: P12931

Pathways: JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling