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SPRED2 antibody (AA 140-190)

SPRED2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990997
  • Target See all SPRED2 Antibodies
    SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
    Binding Specificity
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-190
    Reactivity
    • 19
    • 19
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    • 4
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPRED2 antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.
    Purification
    Spred2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Spred2 antibody was raised against a 13 amino acid synthetic peptide near the center of the human Spred2. The immunogen is located within amino acids 140 - 190 of Spred2.
    Isotype
    IgG
    Top Product
    Discover our top product SPRED2 Primary Antibody
  • Application Notes
    Spred2 antibody can be used for detection of Spred2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Spred2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    Spred2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
    Alternative Name
    Spred2 (SPRED2 Products)
    Synonyms
    SPRED2 antibody, Xspred2 antibody, spred-2 antibody, Xtspred2 antibody, spred2 antibody, wu:fb93f08 antibody, zgc:77284 antibody, Spred-2 antibody, C79158 antibody, sprouty related EVH1 domain containing 2 antibody, sprouty related, EVH1 domain containing 2 antibody, sprouty-related, EVH1 domain containing 2b antibody, sprouty-related, EVH1 domain containing 2 antibody, SPRED2 antibody, spred2 antibody, spred2b antibody, Spred2 antibody
    Background
    Spred2 Antibody: Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.
    Gene ID
    200734
    NCBI Accession
    NP_861449
    UniProt
    Q7Z698
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