ZMYM1 antibody (C-Term)

Catalog No. ABIN6991474

Product Details anti-ZMYM1 Antibody

Target: ZMYM1 (Zinc Finger, MYM-Type 1 (ZMYM1))

Binding Specificity: AA 990-1040, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYM1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: At least two isoforms of ZMYM1 are known to exist, this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members.

Purification: ZMYM1 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZMYM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM1 . The immunogen is located within amino acids 990 - 1040 of ZMYM1.

Isotype: IgG

Application Details

Application Notes: ZMYM1 antibody can be used for detection of ZMYM1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZMYM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZMYM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZMYM1

Target: ZMYM1 (Zinc Finger, MYM-Type 1 (ZMYM1))

Alternative Name: ZMYM1 (ZMYM1 Products)

Synonyms: 5830412B09Rik antibody, AW209050 antibody, MYM antibody, RP11-181E22.4 antibody, zinc finger, MYM domain containing 1 antibody, zinc finger MYM-type containing 1 antibody, Zmym1 antibody, ZMYM1 antibody

Background: ZMYM1 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.

Gene ID: 79830

NCBI Accession: NP_079048

UniProt: Q5SVZ6