FCHSD1 antibody (C-Term)

Catalog No. ABIN6991589

Product Details anti-FCHSD1 Antibody

Target: FCHSD1 (Similar To FCH and Double SH3 Domains 1 (FCHSD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This FCHSD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of FCHSD1 are known to exist. FCHSD1 antibody is predicted to not cross-react with FCHSD2

Purification: FCHSD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: FCHSD1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FCHSD1. The immunogen is located within the last 50 amino acids of FCHSD1.

Isotype: IgY

Application Details

Application Notes: FCHSD1 antibody can be used for detection of FCHSD1 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FCHSD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FCHSD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FCHSD1

Target: FCHSD1 (Similar To FCH and Double SH3 Domains 1 (FCHSD1))

Alternative Name: FCHSD1 (FCHSD1 Products)

Synonyms: NWK2 antibody, A030002D08Rik antibody, FCH and double SH3 domains 1 antibody, Fchsd1 antibody, FCHSD1 antibody

Background: FCHSD1 Antibody: The FCH and double SH3 domains protein 1 (FCHSD1, also known as NWK2) and the related protein FCHSD2 were initially identified in silico as distantly related proteins to FNBP1 and FNBP2. Both share the common domain structure consisting of FCH, FBH, two SH3 and C-terminal proline-rich domains. While little is known of the function of FCHSD1, the related protein NWK is an adaptor protein that is thought to regulate Rho activity downstream of Robo receptors, suggesting that FCHSD1 may be involved in synaptic morphology by regulating actin dynamics in presynaptic terminals.

Molecular Weight: Predicted: 76 kDa

Observed: 82 kDa

Gene ID: 89848

NCBI Accession: NP_258260

UniProt: Q86WN1