CD33 antibody (AA 180-230)
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- Target See all CD33 Antibodies
- CD33
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Binding Specificity
- AA 180-230
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD33 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- At least three isoforms of CD33 are known to exist, this antibody will detect all three isoforms.
- Purification
- CD33 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33. The immunogen is located within amino acids 180 - 230 of CD33.
- Isotype
- IgG
- Top Product
- Discover our top product CD33 Primary Antibody
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- Application Notes
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CD33 antibody can be used for detection of CD33 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- CD33 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- CD33 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- CD33
- Alternative Name
- CD33 (CD33 Products)
- Synonyms
- SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody
- Background
- CD33 Antibody: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.
- Gene ID
- 945
- NCBI Accession
- NP_001763
- UniProt
- P20138
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