Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.
Purification
JAKMIP1 Antibody is affinity chromatography purified via peptide column.
Immunogen
Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.
MGC81051 antibody, Gababrbp antibody, JAMIP1 antibody, MARLIN1 antibody, 5830437M04Rik antibody, C330021K24Rik antibody, Marlin-1 antibody, janus kinase and microtubule interacting protein 1 antibody, janus kinase and microtubule interacting protein 1 L homeolog antibody, janus kinase and microtubule-interacting protein 1 antibody, Celf_2690 antibody, JAKMIP1 antibody, jakmip1.L antibody, LOC100070079 antibody, jakmip1 antibody, LOC100432594 antibody, Jakmip1 antibody
Background
JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.