CCL17 antibody (C-Term)

Catalog No. ABIN6991824

Product Details anti-CCL17 Antibody

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: CCL17 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal CCL17 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CCL17. The immunogen is located within the last 50 amino acids of CCL17.

Isotype: IgG

Application Details

Application Notes: CCL17 antibody can be used for detection of CCL17 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCL17 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CCL17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for CCL17

Target: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Alternative Name: CCL17 (CCL17 Products)

Synonyms: A-152E5.3 antibody, ABCD-2 antibody, SCYA17 antibody, TARC antibody, CCL17 antibody, Abcd-2 antibody, Scya17 antibody, Scya17l antibody, Tarc antibody, abcd2 antibody, C-C motif chemokine ligand 17 antibody, chemokine (C-C motif) ligand 17 antibody, ATP-binding cassette sub-family D member 2 antibody, CCL17 antibody, Ccl17 antibody, LOC100537809 antibody

Background: CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.

Molecular Weight: 10 kDa

Gene ID: 6361

NCBI Accession: NP_002978

UniProt: Q92583