WFDC2 antibody (N-Term)

Catalog No. ABIN6991897

Product Details anti-WFDC2 Antibody

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: WFDC2 antibody is human specific. Multiple isoforms of WFDC2 are known to exist.

Purification: WFDC2 Antibody is affinity chromatography purified via peptide column.

Immunogen: WFDC2 antibody was raised against a 16 amino acid peptide near the amino terminus of human WFDC2. The immunogen is located within the first 50 amino acids of WFDC2 .

Isotype: IgG

Application Details

Application Notes: WFDC2 antibody can be used for detection of WFDC2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: WFDC2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: WFDC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for WFDC2

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Alternative Name: WFDC2 (WFDC2 Products)

Synonyms: WFDC3 antibody, WFDC2 antibody, si:ch211-153a8.3 antibody, EDDM4 antibody, HE4 antibody, WAP5 antibody, dJ461P17.6 antibody, 1600023A02Rik antibody, re4 antibody, CE4 antibody, BE-20 antibody, WAP four-disulfide core domain 2 antibody, WFDC2 antibody, wfdc2 antibody, Wfdc2 antibody

Background: The WAP four-disulfide core domain protein 2 (WFDC2), also known as epididymal protein 4, is a member of the WFDC domain family, a family of proteins that is characterized by the presence of Whey Acidic Protein (WAP) domain, and is highly expressed in the lung and salivary gland (1,2). Members of this family include SLPI and elafin, antiproteinases involved in the innate immune system (2). WFDC2 has been proposed to play a critical role in tumor formation and growth in ovarian cancer cells through the regulation of growth- and apoptosis-associated genes and may thus be a potential therapeutic target for epithelial ovarian cancer (3).

Molecular Weight: Predicted: 14 kDa

Observed: 20kDa

Gene ID: 10406

NCBI Accession: NP_006094

UniProt: Q14508