APPBP2 antibody (C-Term)

Catalog No. ABIN6991929

Product Details anti-APPBP2 Antibody

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APPBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist, this antibody will detect both isoforms.

Purification: APPBP2 antibody is affinity chromatography purified via peptide column.

Immunogen: APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.

Isotype: IgG

Application Details

Application Notes: APPBP2 antibody can be used for detection of APPBP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: APPBP2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for APPBP2

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Alternative Name: APPBP2 (APPBP2 Products)

Synonyms: HS.84084 antibody, PAT1 antibody, 1300003O07Rik antibody, AI465480 antibody, zgc:76971 antibody, wu:fb78e11 antibody, wu:fc25c09 antibody, APPBP2 antibody, DKFZp459F0530 antibody, amyloid beta precursor protein binding protein 2 antibody, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 antibody, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 S homeolog antibody, APPBP2 antibody, Appbp2 antibody, appbp2 antibody, appbp2.S antibody

Background: The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).

Molecular Weight: Predicted: 64 kDa

Observed: 57 kDa

Gene ID: 10513

NCBI Accession: NP_006371

UniProt: Q92624