SLC29A1 antibody (AA 240-290)

Catalog No. ABIN6992115

Product Details anti-SLC29A1 Antibody

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Binding Specificity: AA 240-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC29A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: SLC29A1 antibody is human specific. SLC29A1 antibody is predicted to not cross-react with other SLC29 proteins.

Purification: SLC29A1 antibody is affinity chromatography purified via peptide column.

Immunogen: SLC29A1 antibody was raised against a 17 amino acid peptide near the center of human SLC29A1. The immunogen is located within amino acids 240 - 290 of SLC29A1.

Isotype: IgG

Application Details

Application Notes: SLC29A1 antibody can be used for detection of SLC29A1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLC29A1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SLC29A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SLC29A1

Target: SLC29A1 (Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1))

Alternative Name: SLC29A1 (SLC29A1 Products)

Synonyms: ENT1 antibody, rENT1 antibody, 1200014D21Rik antibody, AA407560 antibody, solute carrier family 29 member 1 (Augustine blood group) antibody, solute carrier family 29 member 1 antibody, solute carrier family 29 (nucleoside transporters), member 1 antibody, SLC29A1 antibody, Slc29a1 antibody

Background: SLC29A1 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A1 is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A1 plays an important role in the uptake of nucleoside-based anti-cancer drugs, polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).

Molecular Weight: Predicted: 50 kDa

Observed: 53 kDa

Gene ID: 2030

NCBI Accession: NP_004946

UniProt: Q99808

Pathways: Carbohydrate Homeostasis, Synaptic Membrane