HOPX antibody (N-Term)

Catalog No. ABIN6992122

Product Details anti-HOPX Antibody

Target: HOPX (HOP Homeobox (HOPX))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: HOPX antibody is human specific. At least three isoforms of HOPX are known to exist, this antibody will detect all three isoforms.

Purification: HOPX antibody is affinity chromatography purified via peptide column.

Immunogen: HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX. The immunogen is located within the first 50 amino acids of HOPX.

Isotype: IgG

Application Details

Application Notes: HOPX antibody can be used for detection of HOPX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: HOPX antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: HOPX antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX (HOPX Products)

Synonyms: CAMEO antibody, HOD antibody, HOP antibody, LAGY antibody, NECC1 antibody, OB1 antibody, SMAP31 antibody, TOTO antibody, 1110018K11Rik antibody, 1200015P04Rik antibody, 2300002F06Rik antibody, AI848177 antibody, AW490897 antibody, Cameo antibody, Hdop antibody, Hod antibody, Hop antibody, Ob1 antibody, Obl antibody, Toto antibody, GIIg15b antibody, HOPX antibody, hod antibody, hop antibody, ob1 antibody, lagy antibody, toto antibody, cameo antibody, necc1 antibody, smap31 antibody, MGC147344 antibody, HOP homeobox antibody, HOPX antibody, Hopx antibody, hopx antibody

Background: HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).

Molecular Weight: Predicted: 12 kDa

Observed: 18 kDa

Gene ID: 84525

NCBI Accession: NP_001138932

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation