GSK3 beta antibody (AA 122-375)

Catalog No. ABIN7435478

Product Details anti-GSK3 beta Antibody

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Binding Specificity: AA 122-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to Glycogen Synthase Kinase 3 Beta (GSK3b)

Specificity: The antibody is a rabbit polyclonal antibody raised against GSK3b. It has been selected for its ability to recognize GSK3b in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Glycogen Synthase Kinase 3 Beta (GSK3b) corresdonding to Lys122~Thr375 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

1:270-1100 Immunohistochemistry: 5-20 μg/mL

1:27-110 Immunocytochemistry: 5-20 μg/mL

1:27-110 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for GSK3 beta

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Alternative Name: Glycogen Synthase Kinase 3 Beta (GSK3b Products)

Synonyms: GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody

Background: Serine/threonine-protein kinase GSK3B

Pathways: WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect