GSK3 beta antibody

Catalog No. ABIN7531588

Product Details anti-GSK3 beta Antibody

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 beta antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: GSK3β Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human GSK3beta.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSK3 beta

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Alternative Name: GSK3B (GSK3b Products)

Synonyms: GSK3 antibody, GSK-3 antibody, C86142 antibody, GSK-3beta antibody, 7330414F15Rik antibody, 8430431H08Rik antibody, GSK3beta antibody, fk80d11 antibody, GSK-3[b] antibody, wu:fb68h05 antibody, wu:fk80d11 antibody, gsk-3 antibody, gsk3 antibody, gsk3-beta antibody, gsk3beta antibody, xgsk-3 antibody, glycogen synthase kinase 3 beta antibody, glycogen synthase kinase 3 beta L homeolog antibody, GSK3B antibody, Gsk3b antibody, gsk3b antibody, gsk3b.L antibody

Background: The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.,GSK3B,gsk-3β,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Regulation of eIF2,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centrosome,G1/S Checkpoint,Cell Adhesion,Microtubules,Hedgehog Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Carbohydrate metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Other Neurological disorders,Stem Cells,Cardiovascular,Heart,Hypertrophy,Akt downstream targets,GSK3B

Molecular Weight: 46kDa/48kDa

Gene ID: 2932

UniProt: P49841

Pathways: WNT Signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect