AIMP2 antibody
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- Target See all AIMP2 Antibodies
- AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AIMP2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein
- Isotype
- IgG
- Top Product
- Discover our top product AIMP2 Primary Antibody
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- Application Notes
- WB 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
- Alternative Name
- AIMP2 (AIMP2 Products)
- Synonyms
- jtv1 antibody, MGC53242 antibody, pro0992 antibody, JTV1 antibody, JTV-1 antibody, P38 antibody, AA407136 antibody, AA407225 antibody, Aimp2(p38) antibody, Jtv1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody, aimp2.L antibody, aimp2 antibody, AIMP2 antibody, Aimp2 antibody
- Background
- Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
- Molecular Weight
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Observed_MW: 35 kDa
Calculated_MW: 35 kDa
- UniProt
- Q13155
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