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GRPR antibody

GRPR Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7238063
  • Target See all GRPR Antibodies
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Reactivity
    • 42
    • 13
    • 11
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 42
    • 1
    • 1
    Rabbit
    Clonality
    • 43
    • 1
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRPR antibody is un-conjugated
    Application
    • 19
    • 16
    • 13
    • 8
    • 8
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human GRPR
    Isotype
    IgG
    Top Product
    Discover our top product GRPR Primary Antibody
  • Application Notes
    WB 1:200-1:1000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.1 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
    Alternative Name
    GRPR (GRPR Products)
    Synonyms
    GRPR antibody, GRP-R antibody, gastrin releasing peptide receptor antibody, GRPR antibody, Grpr antibody
    Background
    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
    Molecular Weight
    43 kDa
    NCBI Accession
    NP_005305
    UniProt
    P30550
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