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IGF2R antibody
IGF2R
Reactivity: Human, Mouse
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IGF2R Antibody
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Target
See all IGF2R Antibodies
IGF2R
(Insulin-Like Growth Factor 2 Receptor (IGF2R))
Reactivity
All reactivities for IGF2R antibodies
Human, Mouse
Host
All hosts for IGF2R antibodies
Rabbit
Clonality
All clonalities for IGF2R antibodies
Polyclonal
Conjugate
All conjugates for IGF2R antibodies
This IGF2R antibody is un-conjugated
Application
All applications for IGF2R antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human IGF2R
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for IGF2R
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Target
IGF2R
(Insulin-Like Growth Factor 2 Receptor (IGF2R))
Alternative Name
IGF2R (IGF2R Products )
Synonyms
CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
Background
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
NCBI Accession
NP_000867
UniProt
P11717
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