ERP44 antibody
Quick Overview for ERP44 antibody (ABIN7244351)
Target
See all ERP44 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Synthetic peptide of human ERP44
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Isotype
- IgG
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Application Notes
- WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
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Alternative Name
- ERP44
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Background
- ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.
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Molecular Weight
- 47 kDa
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NCBI Accession
- NP_055866
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UniProt
- Q9BS26
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Pathways
- Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
Target
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