ZFAND5 antibody

Catalog No. ABIN7245737

Product Details anti-ZFAND5 Antibody

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFAND5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Alternative Name: ZFAND5 (ZFAND5 Products)

Synonyms: 2310057A04Rik antibody, 5830475F03Rik antibody, AA415485 antibody, Za20d2 antibody, Zfp216 antibody, ZA20D2 antibody, ZFAND5A antibody, ZNF216 antibody, wu:fi29f06 antibody, za20d2l antibody, zgc:56057 antibody, za20d2 antibody, zfand5 antibody, zfand5-a antibody, zfand5-b antibody, zfand5a antibody, znf216 antibody, id:ibd2892 antibody, wu:fb16d02 antibody, wu:fc67h07 antibody, zgc:73363 antibody, zinc finger, AN1-type domain 5 antibody, zinc finger AN1-type containing 5 antibody, zinc finger, AN1-type domain 5b antibody, zinc finger AN1-type containing 5 L homeolog antibody, zinc finger, AN1-type domain 5a antibody, Zfand5 antibody, ZFAND5 antibody, zfand5b antibody, zfand5.L antibody, zfand5a antibody

Background: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling