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Endothelin 1 antibody

EDN1 Reactivity: Human, Rat, Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7007190
  • Target See all Endothelin 1 (EDN1) Antibodies
    Endothelin 1 (EDN1)
    Reactivity
    • 100
    • 40
    • 26
    • 18
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 89
    • 33
    • 2
    Rabbit
    Clonality
    • 91
    • 33
    Polyclonal
    Conjugate
    • 51
    • 20
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Endothelin 1 antibody is un-conjugated
    Application
    • 106
    • 58
    • 48
    • 32
    • 26
    • 22
    • 13
    • 13
    • 12
    • 11
    • 11
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human Endothelin 1 (NP_001946.3).
    Isotype
    IgG
    Top Product
    Discover our top product EDN1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Endothelin 1 (EDN1)
    Alternative Name
    Endothelin 1 (EDN1 Products)
    Synonyms
    et1 antibody, et-1 antibody, Edn1 antibody, EDN antibody, ET-1 antibody, ET1 antibody, PPET1 antibody, HDLCQ7 antibody, preproET antibody, Et1 antibody, fb14d01 antibody, wu:fb14d01 antibody, PPET-1 antibody, EDN1 antibody, edn1 antibody, edn1-a antibody, edn1-b antibody, endothelin 1 antibody, endothelin 1 S homeolog antibody, endothelin 1 L homeolog antibody, edn1 antibody, EDN1 antibody, Edn1 antibody, edn1.S antibody, edn1.L antibody
    Background
    This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: 24 kDa

    Calculated_MW: 24 kDa

    Gene ID
    1906
    UniProt
    P05305
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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