Endothelin 1 antibody
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- Target See all Endothelin 1 (EDN1) Antibodies
- Endothelin 1 (EDN1)
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Endothelin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human Endothelin 1 (NP_001946.3).
- Isotype
- IgG
- Top Product
- Discover our top product EDN1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Endothelin 1 (EDN1)
- Alternative Name
- Endothelin 1 (EDN1 Products)
- Synonyms
- et1 antibody, et-1 antibody, Edn1 antibody, EDN antibody, ET-1 antibody, ET1 antibody, PPET1 antibody, HDLCQ7 antibody, preproET antibody, Et1 antibody, fb14d01 antibody, wu:fb14d01 antibody, PPET-1 antibody, EDN1 antibody, edn1 antibody, edn1-a antibody, edn1-b antibody, endothelin 1 antibody, endothelin 1 S homeolog antibody, endothelin 1 L homeolog antibody, edn1 antibody, EDN1 antibody, Edn1 antibody, edn1.S antibody, edn1.L antibody
- Background
- This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 24 kDa
Calculated_MW: 24 kDa
- Gene ID
- 1906
- UniProt
- P05305
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
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