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Amphiregulin antibody

AREG Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256292
  • Target See all Amphiregulin (AREG) Antibodies
    Amphiregulin (AREG)
    Reactivity
    • 32
    • 11
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 9
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 8
    Polyclonal
    Conjugate
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Amphiregulin antibody is un-conjugated
    Application
    • 26
    • 13
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human AREG (NP_001648.1).
    Isotype
    IgG
    Top Product
    Discover our top product AREG Primary Antibody
  • Application Notes
    WB 1:1000-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Amphiregulin (AREG)
    Alternative Name
    AREG (AREG Products)
    Synonyms
    AR antibody, CRDGF antibody, SDGF antibody, Sdgf antibody, AREG antibody, AREGB antibody, AREG/SDGF antibody, amphiregulin antibody, AREG antibody, Areg antibody
    Background
    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.
    Molecular Weight

    Observed_MW: 44 kDa

    Calculated_MW: 27 kDa

    Gene ID
    374
    UniProt
    P15514
    Pathways
    RTK Signaling, EGFR Signaling Pathway
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