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HCK antibody
HCK
Reactivity: Human
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HCK Antibody
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Target
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HCK
(Hemopoietic Cell Kinase (HCK))
Reactivity
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Human
Host
All hosts for HCK antibodies
Rabbit
Clonality
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Polyclonal
Conjugate
All conjugates for HCK antibodies
This HCK antibody is un-conjugated
Application
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Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human HCK (NP_001165600.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IF 1:10-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for HCK
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Target
HCK
(Hemopoietic Cell Kinase (HCK))
Alternative Name
HCK (HCK Products )
Synonyms
laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Gene ID
3055
UniProt
P08631
Pathways
Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Actin Filament Polymerization , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
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