Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PSMC4 antibody

PSMC4 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7010113
  • Target See all PSMC4 Antibodies
    PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
    Reactivity
    • 32
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 5
    Rabbit
    Clonality
    • 28
    • 4
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMC4 antibody is un-conjugated
    Application
    • 21
    • 11
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PSMC4 (NP_006494.1).
    Isotype
    IgG
    Top Product
    Discover our top product PSMC4 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
    Alternative Name
    PSMC4 (PSMC4 Products)
    Synonyms
    NCU02260.1 antibody, AO090003000692 antibody, DDBDRAFT_0188209 antibody, DDBDRAFT_0191435 antibody, DDB_0188209 antibody, DDB_0191435 antibody, MIP224 antibody, RPT3 antibody, S6 antibody, TBP-7 antibody, TBP7 antibody, CIP21 antibody, Tbp7 antibody, 26S protease regulatory subunit 6B antibody, regulatory particle, ATPase-like-3 antibody, 26S proteasome regulatory subunit 6B antibody, proteasome 26S subunit, ATPase 4 antibody, proteasome (prosome, macropain) 26S subunit, ATPase, 4 antibody, LOC732870 antibody, rpt-3 antibody, ATEG_04674 antibody, LELG_01296 antibody, HCAG_00039 antibody, LOC5568998 antibody, GL50803_7950 antibody, EDI_044950 antibody, AOR_1_1218154 antibody, PTRG_03339 antibody, psmC4 antibody, prs6b antibody, LOC100381342 antibody, psmc4 antibody, PSMC4 antibody, Psmc4 antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
    Molecular Weight

    Observed_MW: 47 kDa

    Calculated_MW: 43 kDa/47 kDa

    Gene ID
    5704
    UniProt
    P43686
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
You are here:
Support