DHX36 antibody

Catalog No. ABIN7261201

Product Details anti-DHX36 Antibody

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX36 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DHX36 (NP_065916.2).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DHX36

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Alternative Name: DHX36 (DHX36 Products)

Synonyms: DHX57 antibody, DDX36 antibody, G4R1 antibody, MLEL1 antibody, RHAU antibody, 2810407E23Rik antibody, AI452301 antibody, AU022184 antibody, Ddx36 antibody, mKIAA1488 antibody, DEAH-box helicase 36 antibody, ATP-dependent RNA helicase DHX36 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 36 antibody, Dhx36 antibody, DHX36 antibody, dhx36 antibody, LOC100456222 antibody, LOC100633205 antibody

Background: This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 114 kDa

Calculated_MW: 111 kDa/113 kDa/114 kDa

Gene ID: 170506

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades