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BCL6 antibody

BCL6 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7263151
  • Target See all BCL6 Antibodies
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Reactivity
    • 140
    • 71
    • 26
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 89
    • 51
    • 1
    Rabbit
    Clonality
    • 78
    • 63
    Polyclonal
    Conjugate
    • 67
    • 13
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL6 antibody is un-conjugated
    Application
    • 89
    • 46
    • 34
    • 33
    • 32
    • 17
    • 17
    • 13
    • 13
    • 11
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human BCL6 (NP_001697.2).
    Isotype
    IgG
    Top Product
    Discover our top product BCL6 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Alternative Name
    BCL6 (BCL6 Products)
    Synonyms
    bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
    Background
    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 110 kDa

    Calculated_MW: 72 kDa/78 kDa

    Gene ID
    604
    UniProt
    P41182
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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