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DLL4 antibody (PE)

DLL4 Reactivity: Human FACS Host: Mouse Monoclonal MHD4-46 PE
Catalog No. ABIN7013930
  • Target See all DLL4 Antibodies
    DLL4 (delta-Like 4 (DLL4))
    Reactivity
    • 48
    • 36
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 13
    • 8
    • 1
    • 1
    Mouse
    Clonality
    • 57
    • 21
    Monoclonal
    Conjugate
    • 46
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLL4 antibody is conjugated to PE
    Application
    • 40
    • 28
    • 13
    • 13
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    recombinant soluble human DLL4
    Clone
    MHD4-46
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product DLL4 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    DLL4 (delta-Like 4 (DLL4))
    Alternative Name
    DLL4 (DLL4 Products)
    Synonyms
    hdelta2 antibody, Delta4 antibody, si:ch211-244p18.5 antibody, zgc:136596 antibody, delta like canonical Notch ligand 4 antibody, delta-like 4 (Drosophila) antibody, DLL4 antibody, Dll4 antibody, dll4 antibody
    Background
    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
    Gene ID
    54567
    UniProt
    Q9NR61
    Pathways
    Notch Signaling
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