CEACAM5 antibody (APC)

Catalog No. ABIN7013944

Product Details anti-CEACAM5 Antibody (APC)

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM5 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody CB30 recognizes CD66e (CEA, 180-200 kDa), an extracellular cell surface-bound carcinoembryonic antigen mainly expressed on epithelial cells.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human carcinoembryonic antigen (CEA, CEACAM5)

Clone: CB30

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Alternative Name: CD66e (CEACAM5 Products)

Synonyms: CD66e antibody, CEA antibody, CEACAM5 antibody, CEACAM antibody, 1600029H12Rik antibody, Psg30 antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, carcinoembryonic antigen antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, carcinoembryonic antigen-related cell adhesion molecule 8 antibody, carcinoembryonic antigen gene family antibody, CEACAM5 antibody, Ceacam5 antibody, LOC100409241 antibody, Cea antibody

Background: Carcinoembryonic antigen related cell adhesion mol,The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.,CEACAM5, CEA

Gene ID: 1048

UniProt: P06731