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CD2 antibody (FITC)

CD2 Reactivity: Mouse FACS Host: Rat Monoclonal RM2-5 FITC
Catalog No. ABIN7013990
  • Target See all CD2 Antibodies
    CD2
    Reactivity
    • 151
    • 28
    • 17
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    • 12
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    • 5
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    • 3
    • 3
    • 3
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    • 1
    • 1
    • 1
    Mouse
    Host
    • 121
    • 44
    • 16
    • 2
    Rat
    Clonality
    • 137
    • 44
    • 2
    Monoclonal
    Conjugate
    • 82
    • 20
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    • 6
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD2 antibody is conjugated to FITC
    Application
    • 128
    • 51
    • 51
    • 32
    • 31
    • 28
    • 20
    • 11
    • 10
    • 9
    • 2
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    • 1
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    Flow Cytometry (FACS)
    Specificity
    The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    murine thymocytes
    Clone
    RM2-5
    Isotype
    IgG2b lambda
    Top Product
    Discover our top product CD2 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-3 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    CD2
    Alternative Name
    CD2 (CD2 Products)
    Synonyms
    CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
    Background
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37
    Gene ID
    12481
    UniProt
    P08920
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