AFT7 antibody

Catalog No. ABIN7072916

Product Details anti-AFT7 Antibody

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFT7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ATF7

Application Details

Application Notes: IHC/IF (M,R) 1:800-1:1600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for AFT7

Target: AFT7 (Activating Transcription Factor 7 (AFT7))

Alternative Name: ATF7 (AFT7 Products)

Synonyms: ATFA antibody, 1110012F10Rik antibody, 9430065F09Rik antibody, AI549878 antibody, C130020M04Rik antibody, ATF7 antibody, fa97a09 antibody, fc25b12 antibody, wu:fa97a09 antibody, wu:fc25b12 antibody, atfa antibody, activating transcription factor 7 antibody, activating transcription factor 7b antibody, ATF7 antibody, Atf7 antibody, atf7b antibody, atf7 antibody

Background: ATF7 plays important functions in early cell signaling. Binds the cAMP response element (CRE) , a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.

UniProt: Q8R0S1