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Dystrophin antibody
DMD
Reactivity: Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Dystrophin Antibody
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Target
See all Dystrophin (DMD) Antibodies
Dystrophin (DMD)
Reactivity
All reactivities for Dystrophin antibodies
Mouse, Rat
Host
All hosts for Dystrophin antibodies
Rabbit
Clonality
All clonalities for Dystrophin antibodies
Polyclonal
Conjugate
All conjugates for Dystrophin antibodies
This Dystrophin antibody is un-conjugated
Application
All applications for Dystrophin antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Mouse Dystrophin
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Discover our top product DMD Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC/IF (M,R) 1:600-1:1200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for Dystrophin
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Target
Dystrophin (DMD)
Alternative Name
Dystrophin (DMD Products )
Synonyms
DMD antibody, Dmd antibody, MGC83347 antibody, DKFZp459C1629 antibody, dmd antibody, MGC79631 antibody, DKFZp468A1620 antibody, Dp71 antibody, cb664 antibody, zfDYS antibody, im:6911785 antibody, zgc:110165 antibody, BMD antibody, CMD3B antibody, DXS142 antibody, DXS164 antibody, DXS206 antibody, DXS230 antibody, DXS239 antibody, DXS268 antibody, DXS269 antibody, DXS270 antibody, DXS272 antibody, DXSmh7 antibody, DXSmh9 antibody, Dp427 antibody, dys antibody, mdx antibody, pke antibody, DNADMD1 antibody, RATDMD antibody, CG17750 antibody, CG31175 antibody, CG34157 antibody, CG7240 antibody, CG7243 antibody, CG7344 antibody, DLP antibody, DLP1 antibody, DLP186 antibody, DLP2 antibody, DLP3 antibody, DmDLP antibody, DmDYS antibody, Dmel\\CG34157 antibody, Dp117 antibody, Dp186 antibody, Dp205 antibody, GI3046716 antibody, IDLP antibody, det antibody, dmDLP antibody, dmDp186 antibody, dmDys antibody, dystrophin antibody, dystrophin, gene 1 L homeolog antibody, dystrophin, gene 1 antibody, dystrophin, muscular dystrophy antibody, Dystrophin antibody, DMD antibody, LOC708073 antibody, dmd.1.L antibody, LOC465557 antibody, dmd.1 antibody, dmd antibody, Dmd antibody, Dys antibody
Background
Dystrophin (DMD or BMD) is a large muscle protein whose mutations cause Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), the childhood neuromuscular disorders that result in progressive muscle weakness, respiratory difficulties and cardiovascular dysfunction. Dystrophin is a crucial component of the dystrophin-glycoprotein complex which is essential for muscle membrane integrity and stability. Dystrophin is located on the cytoplasmic face of the sarcolemma and connects the cytoskeletal network to the sarcolemma and extracellular matrix. Multiple isoforms of dystrophin exist due to the alternative splicing, with a wide range of MW (69-72, 110-143, 271, 426 kDa). Most tissues contain transcripts of several isoforms.
Gene ID
13405
NCBI Accession
NP_031894
UniProt
P11531
Pathways
Skeletal Muscle Fiber Development
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