MME antibody (APC-iFluor™700)

Catalog No. ABIN7076804

Product Details anti-MME Antibody (APC-iFluor™700)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is conjugated to APC-iFluor™700

Application: Flow Cytometry (FACS)

Characteristics: The clone FR4D11, a mouse monoclonal antibody recognizes a 100 kDa protein that has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides known as CD10. It is also known as common acute lymphoblastic leukemia antigen (CALLA). CD10 is a type II cell surface glycoprotein typically expressed on acute lymphoblastic leukemias (ALL). Normal, healthy precursors of B and T cells and granulocytes also express CD10. CD10 plays important role in the development process of B cells the in germinal center.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Raji cells

Clone: FR4D11

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10 (MME Products)

Synonyms: CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

Background: The clone FR4D11, a mouse monoclonal antibody recognizes a 100 kDa protein that has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides known as CD10. It is also known as common acute lymphoblastic leukemia antigen (CALLA). CD10 is a type II cell surface glycoprotein typically expressed on acute lymphoblastic leukemias (ALL). Normal, healthy precursors of B and T cells and granulocytes also express CD10. CD10 plays important role in the development process of B cells the in germinal center.

Gene ID: 4311

NCBI Accession: NC_000003

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration