CD47 antibody (FITC)

Catalog No. ABIN7077275

Product Details anti-CD47 Antibody (FITC)

Target: CD47

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD47 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Characteristics: The clone B6H12, a mouse monoclonal antibody selectively recognizes a ~50 kDa N-linked glycan protein originally known as integrin-associated protein or IAP and currently known as CD47. CD47 is an unusual Immunoglobulin (Ig) family member, with an Ig variable-like amino-terminal extracellular domain and a five times membrane-spanning carboxyl-terminal region. It is broadly expressed on the plasma membranes of all hematopoietic cells, including erythrocytes. CD47 plays various important roles in cellular functional processes, including proliferation, apoptosis, adhesion, migration, and also in immune regulation and homeostasis. CD47 is highly expressed on myeloma cells and may be considered as a potential therapeutic candidate for myeloma therapy.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Intact CD47 purified from placenta

Clone: B6H12-2

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD47

Target: CD47

Alternative Name: CD47 (CD47 Products)

Synonyms: IAP antibody, MER6 antibody, OA3 antibody, 9130415E20Rik antibody, AA407862 antibody, AI848868 antibody, AW108519 antibody, B430305P08Rik antibody, Itgp antibody, CD47/IAP antibody, alkaline phosphatase, intestinal antibody, CD47 molecule antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, Cd47 molecule antibody, ALPI antibody, CD47 antibody, Cd47 antibody

Background: The clone B6H12, a mouse monoclonal antibody selectively recognizes a ~50 kDa N-linked glycan protein originally known as integrin-associated protein or IAP and currently known as CD47. CD47 is an unusual Immunoglobulin (Ig) family member, with an Ig variable-like amino-terminal extracellular domain and a five times membrane-spanning carboxyl-terminal region. It is broadly expressed on the plasma membranes of all hematopoietic cells, including erythrocytes. CD47 plays various important roles in cellular functional processes, including proliferation, apoptosis, adhesion, migration, and also in immune regulation and homeostasis. CD47 is highly expressed on myeloma cells and may be considered as a potential therapeutic candidate for myeloma therapy.

Gene ID: 961

UniProt: Q08722