CD79b antibody (PE-Cy7)

Catalog No. ABIN7077448

Product Details anti-CD79b Antibody (PE-Cy7)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79b antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Characteristics: The clone CB3-1, a mouse monoclonal antibody recognizes a 37-39 kD type I integral membrane protein known as CD79. CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and a beta-chain (CD79b). It is noncovalently associated with the CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b expression is exclusive to B lymphocytes and B cell lymphomas. It can be expressed either in the cytoplasm or on the cell surface depending on the maturation state of the B cells. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Purified CD79alphabeta from Ramos B Cell Line

Clone: CB3-1

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b (CD79B Products)

Synonyms: B29 antibody, Ig-beta antibody, Igb antibody, Igbeta antibody, AGM6 antibody, IGB antibody, CD79B antigen antibody, CD79b molecule antibody, Cd79b antibody, CD79B antibody

Background: The clone CB3-1, a mouse monoclonal antibody recognizes a 37-39 kD type I integral membrane protein known as CD79. CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and a beta-chain (CD79b). It is noncovalently associated with the CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b expression is exclusive to B lymphocytes and B cell lymphomas. It can be expressed either in the cytoplasm or on the cell surface depending on the maturation state of the B cells. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.

Gene ID: 974

UniProt: P40259

Pathways: BCR Signaling