Growth Hormone Receptor antibody (AA 551-638)
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- Target See all Growth Hormone Receptor (GHR) Antibodies
- Growth Hormone Receptor (GHR)
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Binding Specificity
- AA 551-638
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Growth Hormone Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human
- Predicted Reactivity
- Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GHR
- Isotype
- IgG
- Top Product
- Discover our top product GHR Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- Growth Hormone Receptor (GHR)
- Alternative Name
- Growth hormone receptor (GHR Products)
- Synonyms
- GHBP antibody, AA986417 antibody, GHR/BP antibody, GHR antibody, ghr antibody, ghr.a antibody, zgc:162141 antibody, growth hormone receptor antibody, growth hormone receptor L homeolog antibody, growth hormone receptor a antibody, GHR antibody, Ghr antibody, ghr.L antibody, ghr antibody, ghra antibody
- Background
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Synonyms: GH receptor, GHBP, GHR, Growth hormone receptor precursor, Serum binding protein, Somatotropin receptor, GHR_HUMAN.
Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway.
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. - Gene ID
- 2690
- UniProt
- P10912
- Pathways
- NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus
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