CD103 antibody
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- Target See all CD103 (ITGAE) Antibodies
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This CD103 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ITGAE/CD103
- Clone
- C4G1
- Isotype
- IgG
- Top Product
- Discover our top product ITGAE Primary Antibody
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- Application Notes
- IHC-P 1:200-400
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
- Alternative Name
- ITGAE/CD103 (ITGAE Products)
- Synonyms
- A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody
- Background
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Synonyms: alpha-E1, alpha-M290, aM290, Antigen CD103, CD 103, CD103, CD103 antigen, HML 1 antigen, HML1 antigen, Human mucosal lymphocyte antigen 1, Human mucosal lymphocyte antigen 1, alpha subunit, Huminae, Integrin alpha E heavy chain, Integrin alpha E light chain, Integrin alpha E, epithelial-associated, Integrin alpha E1, Integrin alpha IEL, Integrin alpha M290, Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide), Integrin, alpha E, ITGAE, MGC141996, MGC183601, Mucosal lymphocyte 1 antigen, Mucosal lymphocyte antigen 1,
Background: Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis
- Gene ID
- 3682
- UniProt
- P38570
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