c-MYC antibody (pSer373) (Biotin)

Catalog No. ABIN7091436

This Rabbit Polyclonal antibody specifically detects c-MYC in WB. It exhibits reactivity toward Human.

Quick Overview for c-MYC antibody (pSer373) (Biotin) (ABIN7091436)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-MYC antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-c-MYC Antibody (Biotin)

Binding Specificity: pSer373

Cross-Reactivity (Details): Fusion Protein

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human C-Myc around the phosphorylation site of Ser373

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: C-Myc

Background:

Synonyms: AU016757, Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, Cellular myelocytomatosis oncogene, MGC105490, MRTL, Myc protein, Myc proto oncogene protein, Myc-related translation/localization regulatory factor, Myc2, myca, Myelocytomatosis oncogene a, Myelocytomatosis oncogene, Niard, Nird, Oncogene Myc, Protooncogene homologous to myelocytomatosis virus, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, v myc avian myelocytomatosis viral oncogene homolog, v myc myelocytomatosis viral oncogene homolog (avian), V-Myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian), zc-myc, MYC_HUMAN.

Background: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

Gene ID: 4609

UniProt: P01106

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect