Liver Arginase antibody
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- Target See all Liver Arginase (ARG1) Antibodies
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Reactivity
- Human, Rat, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Liver Arginase antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Protein A+G purification
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- arginase, liver
- Clone
- 4A0
- Isotype
- IgG2a
- Top Product
- Discover our top product ARG1 Primary Antibody
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- Application Notes
- WB: 1:1000-1:8000, IHC: 1:200-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Alternative Name
- liver Arginase (ARG1 Products)
- Synonyms
- SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody
- Background
- Synonyms:ARG1, Arginase 1, liver Arginase, Liver type arginase Background:Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
- Molecular Weight
- 35 kDa
- Gene ID
- 383
- UniProt
- P05089
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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