BATF2 antibody

Catalog No. ABIN7111947

Product Details anti-BATF2 Antibody

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BATF2 antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: basic leucine zipper transcription factor, ATF-like 2

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for BATF2

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Alternative Name: BATF2 (BATF2 Products)

Synonyms: RGD1311481 antibody, BATF2 antibody, SARI antibody, 4933430F08Rik antibody, basic leucine zipper ATF-like transcription factor 2 antibody, basic leucine zipper transcription factor, ATF-like 2 antibody, Batf2 antibody, BATF2 antibody

Background: Synonyms: Background:AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes(By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.

Molecular Weight: 29 kDa

Gene ID: 116071

UniProt: Q8N1L9