BATF2 antibody (AA 1-189) (HRP)

Catalog No. ABIN7145270

Product Details anti-BATF2 Antibody (HRP)

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Binding Specificity: AA 1-189

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BATF2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BATF2

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Alternative Name: BATF2 (BATF2 Products)

Synonyms: RGD1311481 antibody, BATF2 antibody, SARI antibody, 4933430F08Rik antibody, basic leucine zipper ATF-like transcription factor 2 antibody, basic leucine zipper transcription factor, ATF-like 2 antibody, Batf2 antibody, BATF2 antibody

Background:

Background: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5\'-TGA[CG]TCA-3\' and regulates expression of target genes. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.

Aliases: BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody, B-ATF-2 antibody, Suppressor of AP-1 regulated by IFN antibody, SARI antibody

UniProt: Q8N1L9