×
For best experience we recommend to activate Javascript in your browser.
GRB14 antibody
GRB14
Reactivity: Human, Mouse, Rat
ELISA, WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GRB14 Antibody
(hide)
Target
See all GRB14 Antibodies
GRB14
(Growth Factor Receptor-Bound Protein 14 (GRB14))
Reactivity
All reactivities for GRB14 antibodies
Human, Mouse, Rat
Host
All hosts for GRB14 antibodies
Rabbit
Clonality
All clonalities for GRB14 antibodies
Polyclonal
Conjugate
All conjugates for GRB14 antibodies
This GRB14 antibody is un-conjugated
Application
All applications for GRB14 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
growth factor receptor-bound protein 14
Isotype
IgG
Top Product
Discover our top product GRB14 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for GRB14
(hide)
Target
GRB14
(Growth Factor Receptor-Bound Protein 14 (GRB14))
Alternative Name
GRB14 (GRB14 Products )
Synonyms
GRB14 antibody, AI505286 antibody, growth factor receptor bound protein 14 antibody, GRB14 antibody, grb14 antibody, Grb14 antibody
Background
Synonyms: Background:Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor(INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Molecular Weight
61kd
Gene ID
2888
UniProt
Q14449
Recently viewed
(hide)