IST1 antibody
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- Target See all IST1 Antibodies
- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IST1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- KIAA0174
- Isotype
- IgG
- Top Product
- Discover our top product IST1 Primary Antibody
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- Application Notes
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
- Alternative Name
- IST1 (IST1 Products)
- Synonyms
- 2400003C14Rik antibody, AW536298 antibody, mKIAA0174 antibody, RGD1307799 antibody, OLC1 antibody, fb16b04 antibody, wu:fb16b04 antibody, wu:fi89e07 antibody, zgc:55671 antibody, ist1 antibody, kiaa0174 antibody, pm28 antibody, increased sodium tolerance 1 homolog (yeast) antibody, IST1, ESCRT-III associated factor antibody, increased sodium tolerance 1 homolog S homeolog antibody, Ist1 antibody, IST1 antibody, ist1 antibody, ist1.S antibody
- Background
- Synonyms:KIAA0174 Background:ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells(PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing(PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST(PubMed:23897888).
- Molecular Weight
- 40 kDa
- Gene ID
- 9798
- UniProt
- P53990
- Pathways
- Regulation of Cell Size
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