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MAD2L1 antibody
MAD2L1
Reactivity: Human
WB, ELISA, IHC
Host: Mouse
Monoclonal
8G6
unconjugated
Product Details anti-MAD2L1 Antibody
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Target
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MAD2L1
(MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))
Reactivity
All reactivities for MAD2L1 antibodies
Human
Host
All hosts for MAD2L1 antibodies
Mouse
Clonality
All clonalities for MAD2L1 antibodies
Monoclonal
Conjugate
All conjugates for MAD2L1 antibodies
This MAD2L1 antibody is un-conjugated
Application
All applications for MAD2L1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Purification
Protein A+G purification
Purity
≥95 % as determined by SDS-PAGE
Immunogen
MAD2 mitotic arrest deficient-like 1(yeast)
Clone
8G6
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
WB: 1:1000-1:3000, IHC: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for MAD2L1
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Target
MAD2L1
(MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))
Alternative Name
MAD2L1 (MAD2L1 Products )
Synonyms
HSMAD2 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, bHLHc11 antibody, AA673185 antibody, cb408 antibody, zgc:112133 antibody, mad2 antibody, XMad2 antibody, MAD2L1 antibody, mitotic arrest deficient 2 like 1 antibody, MAX interactor 1, dimerization protein antibody, MAD2 mitotic arrest deficient-like 1 antibody, MAD2 mitotic arrest deficient-like 1 (yeast) antibody, mitotic arrest deficient 2 like 1 S homeolog antibody, MAD2L1 antibody, MXI1 antibody, Mad2l1 antibody, mad2l1 antibody, mad2l1.S antibody
Background
Synonyms:HSMAD2, MAD2, MAD2 like protein 1, MAD2L1 Background:Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Molecular Weight
25-30 kDa
Gene ID
4085
UniProt
Q13257
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