RBPMS antibody

Catalog No. ABIN7118698

Product Details anti-RBPMS Antibody

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPMS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding protein with multiple splicing

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Alternative Name: RBPMS (RBPMS Products)

Synonyms: HERMES antibody, 2010300K22Rik antibody, 2700019M19Rik antibody, AU017537 antibody, hermes antibody, RGD1561067 antibody, si:cabz01079824.1 antibody, RNA binding protein with multiple splicing antibody, RNA binding protein gene with multiple splicing antibody, RNA binding protein with multiple splicing L homeolog antibody, RBPMS antibody, Rbpms antibody, rbpms.L antibody, rbpms antibody

Background: Synonyms:HERMES Background:Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).

Molecular Weight: 28-30 kDa

Gene ID: 11030

UniProt: Q93062