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STAM2 antibody
STAM2
Reactivity: Human, Mouse, Rat
WB, ELISA, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-STAM2 Antibody
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Target
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STAM2
(Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
Reactivity
Human, Mouse, Rat
Host
All hosts for STAM2 antibodies
Rabbit
Clonality
All clonalities for STAM2 antibodies
Polyclonal
Conjugate
All conjugates for STAM2 antibodies
This STAM2 antibody is un-conjugated
Application
All applications for STAM2 antibodies
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
signal transducing adaptor molecule(SH3 domain and ITAM motif) 2
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IP: 1:200-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for STAM2
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Target
STAM2
(Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
Alternative Name
STAM2 (STAM2 Products )
Synonyms
Hbp antibody, STAM2A antibody, STAM2B antibody, 1200004O12Rik antibody, 5730456G07Rik antibody, BB145015 antibody, stam2 antibody, MGC52950 antibody, zgc:103628 antibody, signal transducing adaptor molecule 2 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, signal transducing adaptor molecule 2 S homeolog antibody, STAM2 antibody, Stam2 antibody, stam2.S antibody, stam2 antibody
Background
Synonyms:HBP Background:Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body(MVBs) when complexed with HGS(ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes(By similarity).
Molecular Weight
68 kDa
Gene ID
10254
UniProt
O75886
Pathways
EGFR Signaling Pathway , EGFR Downregulation
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