TEAD4 antibody
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- Target See all TEAD4 Antibodies
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TEAD4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- TEA domain family member 4
- Isotype
- IgG
- Top Product
- Discover our top product TEAD4 Primary Antibody
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- Application Notes
- WB: 1:500-1:2000, IP: 1:200-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
- Alternative Name
- TEAD4 (TEAD4 Products)
- Synonyms
- TEAD4 antibody, rtef1 antibody, tef-3 antibody, eftr-2 antibody, tefr-1 antibody, tcf13l1 antibody, hrtef-1b antibody, xdtef-1 antibody, xlDTEF-1 antibody, RTEF-1 antibody, TEF-1 antibody, TEF-3 antibody, EFTR-2 antibody, RTEF1 antibody, TCF13L1 antibody, TEF3 antibody, TEFR-1 antibody, hRTEF-1B antibody, ETFR-2 antibody, Etfr2 antibody, FR-19 antibody, TEAD-4 antibody, Tcf13r1 antibody, Tef3 antibody, Tefr antibody, Tefr1 antibody, Tefr1a antibody, TEA domain transcription factor 4 antibody, TEA domain transcription factor 4 S homeolog antibody, TEA domain family member 4 antibody, TEAD4 antibody, tead4 antibody, tead4.S antibody, Tead4 antibody
- Background
- Synonyms:RTEF1, TCF13L1, TEF3 Background:Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons'(5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
- Molecular Weight
- 65 kDa
- Gene ID
- 7004
- UniProt
- Q15561
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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