TULP3 antibody

Catalog No. ABIN7120351

Product Details anti-TULP3 Antibody

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TULP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tubby like protein 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TULP3

Target: TULP3 (Tubby Like Protein 3 (TULP3))

Alternative Name: TULP3 (TULP3 Products)

Synonyms: tubl3 antibody, DKFZp469I1734 antibody, TUBL3 antibody, 2310022L06Rik antibody, AI316887 antibody, tubby like protein 3 antibody, tubby-like protein 3 antibody, TULP3 antibody, tulp3 antibody, Tulp3 antibody

Background: Synonyms:Tubby like protein 3, Tubby related protein 3, TUBL3, TULP3 Background:Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A(IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide(phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

Molecular Weight: 56 kDa

Gene ID: 7289

UniProt: O75386

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation